The Best Multi-Country Safari Itineraries in East Africa

There’s something truly magical about East Africa — a region where landscapes unfold like pages from an ancient storybook and wildlife roams freely across borders that exist only on maps. From the snowcapped peaks of Mount Kilimanjaro to the vast plains of the Serengeti, from the gorilla-clad highlands of Uganda and Rwanda to the sun-soaked savannas of Kenya, this part of Africa is the heartbeat of the safari world.

While a single-country safari in Kenya, Tanzania, Uganda, or Rwanda is an unforgettable adventure, combining multiple countries into one seamless itinerary unlocks the full splendor of the region. Multi-country safaris allow travelers to witness the incredible diversity of East Africa — its ecosystems, wildlife, and cultures — all within a single journey. Imagine tracking mountain gorillas in Rwanda one day, watching lions hunt in Kenya’s Maasai Mara the next, and drifting across Tanzania’s Serengeti plains at sunrise.

Here’s a detailed look at the best multi-country safari itineraries in East Africa, carefully crafted for travelers who crave depth, variety, and discovery.

The Classic Kenya–Tanzania Safari: The Great Migration Trail

No combination in Africa is more iconic than Kenya and Tanzania. Together, these two nations share the beating heart of the Great Migration, one of nature’s most breathtaking spectacles. This itinerary follows the migration route — a continuous, circular journey of over two million wildebeests, zebras, and gazelles as they move through the Serengeti and Maasai Mara ecosystems in search of greener pastures.

Suggested Itinerary: 8–10 Days

Days 1–2: Nairobi & Amboseli National Park, Kenya
Begin in Nairobi, where modern Africa meets wild heritage. Visit the Nairobi National Park for a first taste of wildlife before heading south to Amboseli. Framed by the majestic backdrop of Mount Kilimanjaro, Amboseli offers superb elephant sightings, particularly the famous large-tusked bulls that roam freely across the plains.
Days 3–5: Maasai Mara National Reserve, Kenya
The Mara is the crown jewel of Kenya’s safari circuit. Game drives reveal thriving populations of lions, cheetahs, leopards, and countless antelopes. Between July and October, the Great Migration brings dramatic river crossings at the Mara River, as wildebeests plunge into crocodile-filled waters — a once-in-a-lifetime spectacle.
Days 6–10: Serengeti National Park & Ngorongoro Crater, Tanzania
Cross into Tanzania through the Isebania border post and enter the legendary Serengeti, whose endless plains inspired countless wildlife films. Depending on the season, you might find yourself amidst the migration herds or surrounded by predators on the hunt. End the journey at the Ngorongoro Crater, a UNESCO World Heritage Site where an entire ecosystem thrives within the walls of an ancient volcano.

This itinerary offers not only spectacular game viewing but also cultural encounters with the Maasai people, whose deep-rooted traditions continue to define the landscapes of both countries.

Uganda–Rwanda–Tanzania: Primates and Plains Safari

For travelers seeking a blend of wild adventure and deep connection, this tri-country safari is a revelation. It combines the rainforest intimacy of gorilla and chimpanzee trekking in Uganda and Rwanda with the expansive savannas of Tanzania, offering both the emotional thrill of meeting great apes and the grandeur of classic African safari landscapes.

Suggested Itinerary: 10–12 Days

Days 1–3: Bwindi Impenetrable National Park, Uganda
Begin in Uganda, often called the “Pearl of Africa.” Fly into Entebbe and continue to Bwindi in the country’s southwest, where the ancient rainforest shelters nearly half of the world’s remaining mountain gorillas. Trekking through the misty jungle to find a gorilla family is one of life’s most profound wildlife experiences.
Days 4–5: Volcanoes National Park, Rwanda
Cross the Cyanika or Gatuna border into Rwanda and continue your primate journey. Volcanoes National Park, part of the Virunga Massif, offers a chance to track another gorilla family or encounter golden monkeys, a rare and delightful species found only in this region. You can also visit the Dian Fossey Gorilla Fund or hike to her historic research site for a deeper understanding of gorilla conservation.
Days 6–8: Lake Kivu & Kigali
Take a break from trekking and unwind by the shores of Lake Kivu, Rwanda’s most scenic freshwater lake. Kayak between fishing villages or explore nearby islands before heading to Kigali, a city that symbolizes Rwanda’s remarkable transformation. Visit the Kigali Genocide Memorial and browse local art galleries to experience the city’s blend of resilience and creativity.
Days 9–12: Serengeti & Ngorongoro, Tanzania
From Kigali, fly to northern Tanzania to complete your journey in the Serengeti and Ngorongoro Crater. The shift from rainforest to savanna feels like stepping into another world, yet the continuity of awe remains. Watch elephants roam beneath acacias, lions bask in the golden grass, and wildebeests stretch endlessly across the horizon.

This itinerary offers the best of both worlds — the intimate, soulful encounters of Central Africa and the sweeping spectacle of East Africa’s open plains.

Kenya–Uganda: The Savannah and the Silverbacks

Combining Kenya’s classic game parks with Uganda’s gorilla highlands offers an unforgettable contrast — from roaring lions to peaceful gorillas, from sun-drenched savannas to mist-shrouded forests.

Suggested Itinerary: 8–10 Days

Days 1–4: Maasai Mara National Reserve, Kenya
Start your adventure in Kenya’s most famous reserve. Spend three nights in the Maasai Mara, exploring its diverse wildlife and enjoying dawn and dusk game drives that reveal predators, elephants, and colorful birdlife.
Days 5–7: Bwindi Impenetrable National Park, Uganda
Fly from Nairobi to Entebbe, then connect to Bwindi via Kihihi or Kisoro airstrip. Embark on a life-changing trek through the dense rainforest to meet a gorilla family. The experience is emotional, humbling, and unforgettable. In the evening, visit nearby Batwa cultural communities to learn about the forest’s earliest inhabitants.
Days 8–10: Lake Bunyonyi & Return to Entebbe
After the trek, unwind at Lake Bunyonyi, a scenic highland lake surrounded by terraced hills and dotted with islands. Canoe between villages or simply relax as mist drifts over the calm water. End your journey with a return to Entebbe, where you can visit the Uganda Wildlife Education Centre or enjoy a sunset by Lake Victoria.

This itinerary perfectly balances thrill and tranquility — the drama of the Mara and the serenity of the gorillas.

Tanzania–Zanzibar–Kenya: The Bush to Beach Experience

For travelers who crave both adventure and relaxation, this route combines the wild beauty of the savanna with the romance of the Indian Ocean. It’s an itinerary that satisfies every sense — from the roar of lions to the whisper of waves on a white-sand beach.

Suggested Itinerary: 10–14 Days

Days 1–5: Serengeti National Park & Ngorongoro Crater, Tanzania
Begin in northern Tanzania, where the Serengeti delivers world-class game viewing. Depending on the season, witness the migration herds or enjoy tranquil moments watching elephants and big cats. Continue to Ngorongoro Crater for more Big Five encounters surrounded by breathtaking volcanic scenery.
Days 6–9: Zanzibar Island
Fly from Arusha to Zanzibar, the “Spice Island.” Wander through the winding alleys of Stone Town, a UNESCO World Heritage Site rich in Swahili-Arab history. Later, escape to Zanzibar’s pristine beaches — swim in turquoise waters, snorkel among coral reefs, and savor fresh seafood under palm trees.
Days 10–14: Amboseli & Maasai Mara, Kenya
Cross into Kenya and head to Amboseli National Park, famous for its elephant herds and views of Mount Kilimanjaro. Then journey north to the Maasai Mara, where the drama of the African plains unfolds once again. If your timing aligns with the migration, you’ll witness nature’s greatest spectacle before returning to Nairobi for your departure.

This route is the perfect combination of excitement, culture, and relaxation — ideal for honeymooners, photographers, and explorers alike.

Rwanda–Tanzania–Kenya: From Gorillas to the Great Migration

This tri-country itinerary captures the soul of East Africa — from Rwanda’s misty highlands to Tanzania’s golden plains and Kenya’s cultural heart.

Suggested Itinerary: 9–12 Days

Days 1–3: Volcanoes National Park, Rwanda
Begin your adventure in the Virunga Mountains, trekking to see the majestic mountain gorillas. Each encounter reveals the deep intelligence and gentle nature of these rare creatures.
Days 4–7: Serengeti National Park, Tanzania
Fly from Kigali to the Serengeti and dive straight into the wild. Whether you visit during the migration or not, the Serengeti’s open landscapes promise thrilling game drives, luxury tented camps, and mesmerizing sunsets.
Days 8–12: Maasai Mara & Lake Naivasha, Kenya
Cross north into Kenya for more migration action in the Mara or birdwatching along the shores of Lake Naivasha. The combination of wildlife, landscapes, and Maasai culture creates the perfect finale to your East African adventure.

This route captures the region’s diversity — lush forests, open savannas, volcanic highlands, and rich cultural heritage — all in one seamless journey.

Why Multi-Country Safaris Matter

Multi-country safaris in East Africa are not just about ticking destinations off a list — they’re about connection. They show how ecosystems stretch beyond borders, how cultures blend, and how every landscape, from Uganda’s jungles to Tanzania’s plains, plays a role in the story of Africa.

They also allow travelers to maximize their experience. With short flights and well-maintained overland routes, it’s easy to move from one country to another, experiencing different climates, wildlife species, and local traditions along the way.

Each destination complements the other: Kenya and Tanzania for big-game drama, Uganda and Rwanda for primate encounters, Zanzibar for coastal serenity. Together, they form the most complete safari experience imaginable.

Experience the Ultimate East African Safari with Moreen Tours & Travel

To explore the best multi-country safari itineraries in East Africa, travel with Moreen Tours & Travel — your trusted partner in crafting seamless, sustainable, and unforgettable journeys.

With deep regional expertise and personalized service, Moreen Tours & Travel designs cross-border safaris that combine comfort, authenticity, and adventure. Whether you dream of tracking gorillas in Rwanda, witnessing the Great Migration in Kenya and Tanzania, or relaxing on the beaches of Zanzibar, they ensure your journey flows effortlessly from one destination to the next.

When you travel with Moreen Tours & Travel, you’re not just exploring East Africa — you’re experiencing the heart of the continent in motion, one country at a time.